Valeritas' Microneedle Array Patch technology enables drug delivery or interstitial fluid sensing at the epidermis or dermis, without limitations of drug size, structure, charge, or the patient's skin characteristics. Arrays penetrate only the shallow layers of the skin, avoiding close proximity to pain receptors, making the system extremely comfortable for the patient to wear.

Valeritas' Microneedle Array technology consists of multiple small, hollow or solid needles fabricated on a single surface. Microneedles can be constructed of metal or biodegradable polymers. The length, diameter, wall thickness, and shapes can be manufactured to a variety of specifications. Valeritas' proprietary manufacturing processes ensure that these arrays can be fabricated at very low cost.

• Delivery of large proteins, fragile antibodies, and hormones.
• Delivery of small molecules, particularly those with difficulty diffusing through skin layers.
• Delivery of vaccines, both conventional and DNA-based.
• Fluid sensing of glucose, hormones, blood gases, and therapeutic drug levels.

• Simple for patient to use, and fully disposable.
• Unique manufacturing techniques result in very low cost.
• Accurate, reliable delivery of drug to epidermis or dermis, circumventing the stratum corneum.
• Passive or active drug delivery profiles.
• Can be used with Valeritas' e-Patch device to deliver a wide range of drug volumes under various extended or time-release profiles.